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Symbol
Name
ID
Pnpla2
patatin-like phospholipase domain containing 2
MGI:1914103
Phenotype annotations related to cardiovascular system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
cardiovascular system phenotype
abnormal cardiovascular system morphology
pulmonary vascular congestion
increased cardiac muscle glycogen level
increased cardiac muscle triglyceride level
abnormal myocardium layer morphology
abnormal myocardial fiber morphology
abnormal myocardial fiber mitochondrial morphology
abnormal heart morphology
thick interventricular septum
increased heart weight
cardiac hypertrophy
abnormal heart ventricle morphology
increased heart left ventricle weight
dilated heart left ventricle
dilated heart right ventricle
cardiac fibrosis
abnormal cardiovascular system physiology
decreased ventricle muscle contractility
increased heart rate
abnormal myocardial fiber physiology
abnormal cardiomyocyte apoptosis
congestive heart failure
Availability Mouse Genotype
Pnpla2tm1Rze/Pnpla2tm1Rze
Pnpla2tm1Rze/Pnpla2tm1Rze
Tg(Myh6-Pnpla2)94Biat/0
*
Pnpla2tm1Eek/Pnpla2tm1Eek
Tg(Ckmm-cre)5Khn/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory